**There is [an older version](https://doi.org/10.25678/000044) of this dataset.** The dataset contains concentrations profiles of 213 agricultural pesticides in surface water samples. Half-day composite samples were taken from five small streams in Switzerland from the beginning of March to the end of August 2015. Half-day samples from discharge events were measured individually, whereas half-day samples taken during dry weather periods between discharge events were pooled to samples of variable lengths (five days on average) and then measured resulting in 34 to 60 measured samples per site.