Water RNA sequences, qPCR and water quality data. This dataset is associated with the following publication: Linz, D., I. Struewing, N. Sienkiewicz, R. Labiosa, and J. Lu. Metatranscriptomics reveals gene expression dynamics during an anatoxin-a producing Dolichospermum bloom in a western coastal lake. CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 372: 144124, (2025).